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SILVER SPRING, La. (AP) — Two drugs that can make you more likely to suffer from erectile dysfunction could soon be approved by the Food and Drug Administration for their use in treating erectile dysfunction.

Viagra Connect and Cialis are both drugs that help treat erectile dysfunction. They’re both prescribed for the treatment of male sexual dysfunction in men.

Viagra is used by roughly 80 percent of men, according to the FDA. Cialis is prescribed to men ages 18 to 64 and is the least commonly prescribed ED drug. That’s because the drug does not make you erectable — which is why it’s often prescribed for erectile dysfunction.

The FDA has not approved the two drugs in any way, but the drug is still under investigation. According to the agency, the FDA hasn’t approved the use of Cialis to treat erectile dysfunction, but that could change. The agency also hasn’t approved the use of Viagra Connect to treat erectile dysfunction.

A new study published in the Journal of Sexual Medicine in November found that the two drugs didn’t significantly differ in their ability to improve erectile function. Researchers at Harvard Medical School found that the two drugs were equally effective, but the researchers found that the drugs were not better for those who were treated with Viagra.

The researchers also found that the drugs didn’t significantly improve erectile function. The drugs had a small effect on men with ED and a larger effect on those who had ED, they said.

A separate study published in the journal looked at the effectiveness of Viagra Connect and Cialis in men with ED, and found no benefit.

“In terms of effectiveness, we found that those who were treated with both Viagra and Cialis who were using Viagra had a small improvement in their ability to perform sexually,” said Dr. Steven Nissen, a spokesman for the company. “This shows that in men with ED, it is important to try these drugs as prescribed, and we are excited about our findings.”

Viagra, which is the brand name of the drug, is also a treatment for impotence, a condition in which a man cannot get and keep an erection. A study of Viagra’s effectiveness in men with ED found that the two drugs were equally effective, but the researchers found that the drugs were not better for those who were treated with the drug.

“There’s not enough data to support the claims that these drugs are better for impotence,” Nissen said.

A second study published in November found that the drug, known by its generic name sildenafil, was effective in treating ED in men with ED. Researchers at the University of Utah found that men who took one of the drugs had a significantly lower rate of ED.

The FDA has not approved Viagra Connect to treat erectile dysfunction, but that could change. The agency also hasn’t approved it to treat ED, but that could change.

The study’s authors wrote in an e-mail alert: “While the effectiveness of these two drugs is the same, we think it is important to note that the drugs have slightly different mechanisms of action. It is not possible to determine directly whether these drugs are more effective or have a different mechanism of action,” the authors added.

The two drugs have side effects and Viagra’s active ingredient is sildenafil. The drug is the brand name of sildenafil, and it’s sold under the generic name tadalafil. Sildenafil is the brand name of vardenafil, and it’s sold under the brand name vardenafil-flavon. Vardenafil is sold as a generic, and it’s not available in the U. S.

Viagra and Cialis are approved for use in men who have erectile dysfunction. Cialis is approved for use in men 18 to 64 years old and should be prescribed by a doctor.

In a separate study in the New England Journal of Medicine, researchers examined the effectiveness of Viagra and Cialis in men with erectile dysfunction. They found that the drugs were equally effective, but the researchers found that the drugs were not better for those who were treated with Viagra and Cialis.

“This is an excellent result, but we are still investigating the use of Viagra,” Nissen said.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you have any questions or concerns about taking Cialis, consult your doctor or pharmacist. Cialis is a prescription medication used to treat benign prostatic hyperplasia (BPH) and isosorbide dinitrate-type hypertension. BPH and BPH-tension are common side effects of Cialis, particularly for men with lower urinary tract symptoms (LUTS).anchez genotoxicity (COTAL_RHYDRO + CYP2D6 - CYF3A4).

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If you experience any serious side effects, such as:

  • If you breathe more air
  • If you have had an allergic reaction to Cialis or any other medications, including prescription drugs
  • If you are pregnant or think will become pregnant (pulmonary hypertension)
  • If you have any kidney problems
  • If you are taking any supplements or medications
  • If you or your partner plan on becoming pregnant

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Cialis Do you have Tadalafil crystals in your penis? We can help you tell your doctor if you are experiencing signs of a side effect, such as erectile dysfunction or erectile dysfunction. Tadalafil can cause potentially serious adverse reactions when taken in ways that can be extremely severe.

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